Discover Precision in Single Cell Isolation

Revolutionize Your Research with Advanced Cell Isolation with ARRALYZE

The protocol for single cell isolation involves the separation of individual cells from a heterogeneous population. Single cell isolation is often a must to fulfill regulatory requirements for the detection of monoclonality in biological research and development.

However, the conventional separation technique using 96-well plates and other standard formats for single cell isolation is unreliable and very slow. Scanning 96-well plates requires hundreds to thousands of images, making the process extremely slow and increasing the likelihood of missing individual cells. Therefore, the traditional workflow of spreading the cells into wells, growing, imaging, and isolating takes weeks to ensure monoclonality of the cells.

Technology of Single Cell Isolation

ARRALYZE^® nano-well glass microarrays are ideal because they allow us to see the entire well with one field of view, enabling rapid imaging with 100% reliability. With our platform, you can ensure monoclonality quickly and accurately without having to repeat the process as with the conventional technique. This accuracy and reliability saves time and increases productivity.

Thanks to the advanced technology of ARRALYZE^® nano-well glass microarrays, the process of single cell isolation is fast, extremely reliable and confirmable with the single cell dispersion technique. This simplifies the single cell isolation process and significantly shortens development times. In addition, the optical properties of glass also enable the highest image quality.

Identifying and isolating specific cells has traditionally been a labor-intensive and time-consuming process, often requiring multiple manual steps. Our CellShepherd system revolutionizes this workflow, offering a more streamlined and efficient solution. One of the standout features is its ability to gently and precisely isolate individual cells, ensuring optimal conditions for downstream processes like cell expansion or further analysis such as genomics.

The footage, captured in real-time, showcases the cell isolation unit delicately isolating a single cell with unparalleled accuracy—ensuring minimal disturbance to the cell throughout the process.

Key Features of
Single Cell Isolation

CellShepherd^® has the following advantages for single cell isolation:

Precise isolation of single cells from heterogeneous cell populations
Isolation of the contents of wells while maintaining high viability
Non-destructive process to preserve cell integrity
Single cell dispensing ensures precise deposition, high immobilization efficiency, and easy recovery for single cell analysis
Perform single cell isolation with live experiments on the specialized nanowell glass array precise spatial confinement of cells
Perform high throughput single cell isolation on a small footprint with a high aspect ratio that produces thousands of wells
Isolation of single cells for further processing
Gentle extraction of single cells and supernatants
Easily extract single cells from the cluster of heterogeneous cells with real-time imaging and single cell printing
Layouts optimized for single cell screening allow scientists to adjust the size and shape of wells for single cell isolation depending on cell type and experiment
Gain insight into every phase of biological experiments during single cell isolation in nanowells