Capture Dynamic Cellular Interactions

Discover the Power of Live Cell Imaging with ARRALYZE

Live cell imaging is an innovative technique in modern biological research that enables direct and detailed observations of the complex processes in living cells. However, documenting these dynamic processes comes with some obstacles, such as maintaining cell viability and obtaining high-resolution images without compromising cellular integrity.
CellShepherd's unique wells enable researchers to perform real-time cellular microscopy, single cell imaging, and live cell screening. Our nanowell glass microarray facilitates cell screening and analysis with live cell imaging systems and live cell microscopy.

Key Features of Cell Imaging

CellShepherd is capable of precise and accurate cell measurements as well as multiple live cell imaging. It has the following key features for live cell imaging:

Suitable for multiple microscopes: CellShepherd nanowells glass arrays can be used with fluorescence, brightfield, and other microscopes for detailed analysis
Gain cellular detail with single cell imaging:
Distinguish single cells from each other with live cell microscopy
Perform high-content screening with single cell resolution of the live cell assay
Advanced real-time imaging capabilities, including a brightfield microscope and three fluorescence channels.
Isolation of single cells for downstream processing, gentle and alive
Precise dosing of cell suspensions with excellent viability
AI-driven analysis for automated cell counting and tracking
User-friendly interface for easy setup, monitoring, and analysis of experiments

Time-lapse video of bovine dedifferentiated fat cell adherence. Images were captured 10 minutes after application and span 90 minutes. Adherence starts between 20 and 30 minutes and completes at 60 minutes, demonstrating the effectiveness of automated imaging for time-resolved single-cell assays.

Technology of Cell Imaging

A rough sketch how
imaging is done with Arralyze

One of the outstanding features of the ARRALYZE CellShepherd^® nanowell glass microarray is the ability to create deep wells that physically immobilize cells, which is particularly advantageous for live cell applications that require monoclonality. This level of customization of well shapes and sizes increases the versatility of the microfluidic glass devices, which are suitable for a wide range of assays.

The ARRALYZE CellShepherd^® nanowell glass microarray revolutionizes live cell imaging with its advanced laser-induced deep etching (LIDE) technology. A glass microarray fabricated with LIDE technology exhibits a high aspect ratio without its structure being affected by stress or micro defects. Glass-based microarrays are the perfect choice for live cell imaging because they provide an inert environment for experiments and the right properties for live cell fluorescence microscopy, real-time microscopy, and high-quality cellular microscopy.

Live Cell Imaging

Take advantage of our innovative cell imaging technology

Discover the benefits of live cell observation to achieve breakthroughs in biological research and beyond

Applications of Cell Imaging

Cell imaging with CellShepherd^® can do the following:

Drug Development

Monitor cell fate with live cell imaging for drug screening in cell-based assays, early safety evaluation, and mode-of-action studies.

Cell Line Development

Track cell growth and clonal expansion with real-time microscopy and gain important insights into the subcellular mechanisms of the living cell as it grows. Understanding cellular proliferation is crucial in cancer research, stem cell research, and drug development.