Single Cell Screening Rethought
Functional assays with live cell monitoring
Nanowell Glass Arrays
Wells with high-aspect ratios
The core of the ARRALYZE® advantage is our glass array technology. Our innovative proprietary manufacturing process enables us to produce absolutely defect-free small features with high aspect ratios in standard glass types.
Holistic Approach
Seamless workflow
Around these glass arrays we have built a single cell dispenser, an inverted microscope and a cell extraction unit - in only one device.
Downstream Processes
Do not stop at collecting data
With the cell extraction unit you can then extract hits alive in a controlled manner for downstream processes.
The CellShepherd
Most versatile single screening device
This device- the CellShepherd® - enables you to screen large cell populations on the single cell level in a streile environment to identify the most outstanding cells. The microscope allows you to monitor functional assays live and reveal data not accessible otherwise - including cell-cell interactions.
ARRALYZE Advantages
Live Optical Analysis
Follow the full evolution of your experiments!
Important data can be gained at any stage of biological experiments. The end result might be what you are mainly after, but immediate reactions of the cells to a drug or observing cell-cell interaction on the single cell level might be an insight not accessible with other techniques yet. The CellShepherd® allows for the microscopic analysis of processes inside the microwells at any time: take snapshots, videos and time-lapse series to follow the development of your experiment as detailed as you wish.
Smaller Features
No need to compromise on the number of experiments!
Our glass wells require very low sample volumes ranging of picoliters to nanoliters, which reduces use of expensive reagents per experiment. The well dimensions have an ideal fit to the size of individual cells and cell clusters, making it easy to find and track cells - a critical feature for high-throughput experiments. The low footprint of the glass arrays allows for a greater number of experiments per area, reducing the overall footprint per experiment. This way you can increase the statistical significance of your experiments in a very economical manner.
Inert Matrix
You should trust your experimental results!
The most critical factor of any study are reliable and reproducible measurements. Avoiding contamination is key and can only be guaranteed by inert and stable materials. However, many systems rely on using non-inert materials thus risking the diffusion of reagents and drugs. These effects may be small but can compromise or even devaluate your whole experiment. ARRALYZE arrays consist entirely of glass, one of the most inert materials in bio sciences.
Customizable Arrays
We put freedom of design back into your assays!
With standard assays, your experiments have to be adapted to existing equipment. We believe that the equipment should follow the design of your experiment. With ARRALYZE you can tailor the size and shape of the wells to your cell type and the requirements of the assay. You can also study single cells, clusters of cells or co-cultures in different arrangements. Besides the well size and shape you can of course also pick the format of your glass array such as the microscope slide format.
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